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1

Regioselektive Synthese und antivirale Wirksamkeit von an N7 acyclisch substituierten Purinnucleosid-Analoga

Dr. Gerhard Jähne, Herbert Kroha, Armin Müller, Dr. Matthias Helsberg, Dr. Irvin Winkler, Dr. Gerhard Gross, Dr. Thomas Scholl

Journal:

Angewandte Chemie

Year:

1994

File:

PDF, 379 KB

1994

2

Regioselective Synthesis and Antiviral Activity of Purine Nucleoside Analogues with Acyclic Substituents at N7

Dr. Gerhard Jähne, Herbert Kroha, Armin Müller, Dr. Matthias Helsberg, Dr. Irvin Winkler, Dr. Gerhard Gross, Dr. Thomas Scholl

Journal:

Angewandte Chemie International Edition

Year:

1994

Language:

english

File:

PDF, 244 KB

english, 1994

3

Preparation of carbocyclic phosphonate nucleosides

Gerhard Jähne, Armin Müller, Herbert Kroha, Manfred Rösner, Otto Holzhäuser, Christoph Meichsner, Matthias Helsberg, Irvin Winkler, Günther Rieß

Journal:

Tetrahedron Letters

Year:

1992

Language:

english

File:

PDF, 305 KB

english, 1992

4

In VitroSelection for Different Mutational Patterns in the HIV-1 Reverse Transcriptase Using High and Low Selective Pressure of the Nonnucleoside Reverse Transcriptase Inhibitor HBY 097

Jörg-Peter Kleim, Irvin Winkler, Manfred Rösner, Reinhard Kirsch, Helga Rübsamen-Waigmann, Arno Paessens, Günther Riess

Journal:

Year:

1997

Language:

english

File:

PDF, 89 KB

english, 1997

5

Changes of the nucleic acid patterns in the two types of eggs of Formica polyctena queens (ins. hym. form.) differently predisposed during embryogenesis

Gerhard H. Schmidt, Irvin Winkler

Journal:

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry

Year:

1991

Language:

english

File:

PDF, 1.31 MB

english, 1991

6

Structures of Tyr188Leu mutant and wild-type HIV-1 reverse transcriptase complexed with the non-nucleoside inhibitor HBY 097: inhibitor flexibility is a useful design feature for reducing drug resistance

Yu Hsiou, Kalyan Das, Jianping Ding, Arthur D. Clark Jr, Jörg-Peter Kleim, Manfred Rösner, Irvin Winkler, Günther Riess, Stephen H. Hughes, Edward Arnold

Journal:

Journal of Molecular Biology

Year:

1998

Language:

english

File:

PDF, 1.55 MB

english, 1998

7

Antiviral activity and pharmacokinetics of HOE 602, an acyclic nucleoside, in animal models

Irvin Winkler, Erhardt Winkelmann, Scholl Thomas, Rösner Manfred, Jähne Gerhard, Helsberg Matthias

Journal:

Antiviral Research

Year:

1990

Language:

english

File:

PDF, 610 KB

english, 1990

8

Retention of marked sensitivity to (S)-4-isopropoxycarbonyl-6-methoxy-3-(methylthiomethyl)-3,4-Dihydroquinoxaline-2(1H)-Thione (HBY 097) by an azidothymidine (AZT)-resistant human immunodeficiency virus type 1 (HIV-1) strain subcultured in the combined presence of quinoxaline HBY 097 and 2′,3′-dideoxy-3′-thiacytidine (Lamivudine)

Jan Balzarini, Heidi Pelemans, Gunther Riess, Manfred Roesner, Irvin Winkler, Erik De Ckrcq, Jörg-Peter Kleim

Journal:

Biochemical Pharmacology

Year:

1998

Language:

english

File:

PDF, 1.09 MB

english, 1998

9

Changing of the protein pattern in the two types of eggs of Formica polyctena (Foerster) queens (ins., hym., form.) differently predisposed during embryogenesis

Winkler, Irvin, Schmidt, Gerhard H.

Journal:

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry

Year:

1988

Language:

english

File:

PDF, 1.54 MB

english, 1988

10

COMBINED SECTIONS OF GYNÆCOLOGY AND OBSTETRICS AND PATHOLOGY.

Scmmidt, Gerhard H., Winkler, Irvin

Journal:

Year:

1912

Language:

english

File:

PDF, 886 KB

english, 1912

11

Macromolecular changes during oogenesis of Formica polyctena (Foerster) (Ins., Hym., Form.): A case of two types of eggs differently predisposed

Scmmidt, Gerhard H., Winkler, Irvin

Journal:

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry

Year:

1984

Language:

english

File:

PDF, 913 KB

english, 1984

12

Selective Pressure of a Quinoxaline Nonnucleoside Inhibitor of Human Immunodeficiency Virus Type 1 (HIV-1) Reverse Transcriptase (RT) on HIV-1 Replication Results in the Emergence of Nucleoside RT-Inhibitor-Specific (RT Leu-74 → Val or Ile and Val-75 → Leu or Ile) HIV-1 mutants

Jörg-Peter Kleim, Manfred Rösner, Irvin Winkler, Arno Paessens, Reinhard Kirsch, Yu Hsiou, Edward Arnold and Günther Riess

Journal:

Proceedings of the National Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 346 KB

english, 1996

13

Secondary metabolites by chemical screening. 17. Nigericinol derivatives: synthesis, biological activities and modeling studies

Grabley, Susanne, Hammann, Peter, Klein, Robert, Seibert, Gerhard, Winkler, Irvin, Kroeger, Achim, Ditzel, Frank

Journal:

Journal of Medicinal Chemistry

Year:

1992

Language:

english

File:

PDF, 706 KB

english, 1992

14

Antiviral Activity of the Human Immunodeficiency Virus Type 1–Specific Nonnucleoside Reverse Transcriptase Inhibitor HBY 097 Alone and in Combination with Zidovudine in a Phase II Study

Kleim, Jörg‐Peter, Winters, Mark, Dunkler, Anke, Suarez, José‐Ramon, Rieß, Günther, Winkler, Irvin, Balzarini, Jan, Oette, Dagmar, Merigan, Thomas C.

Journal:

The Journal of Infectious Diseases

Year:

1999

Language:

english

File:

PDF, 110 KB

english, 1999

15

Polyclonal antibodies to mannan from yeast also recognize the carbohydrate structure of gp120 of the AIDS virus

Müller, Werner EG., Schröder, Heinz C., Reuter, Petra, Maidhof, Armin, Uhlenbruck, Gerd, Winkler, Irvin

Journal:

Year:

1990

File:

PDF, 298 KB

1990

16

Inhibition of HIV and virus replication by polysulphated polyxylan

Biesert, Lothar, Suhartono, Hary, Winkler, Irvin, Meichsner, Christoph, Helsberg, Matthias, Hewlett, Guy, Klimetzek, Volker, Mölling, Karin, Schlumberger, Horst-Dieter, Schrinner, Elmar, Brede, Hans-D

Journal:

Year:

1988

File:

PDF, 1.34 MB

1988

17

Antiviral Activity of the Human Immunodeficiency Virus Type 1-Specific Nonnucleoside Reverse Transcriptase Inhibitor HBY 097 Alone and in Combination with Zidovudine in a Phase II Study

Jörg-Peter Kleim, Mark Winters, Anke Dunkler, José-Ramon Suarez, Günther Rieβ, Irvin Winkler, Jan Balzarini, Dagmar Oette and Thomas C. Merigan

Journal:

The Journal of Infectious Diseases

Year:

1999

Language:

english

File:

PDF, 948 KB

english, 1999

18

Cefodizime, an aminothiazolyl cephalosporin. IV. Influence on the immune system.

LIMBERT, MICHAEL, BARTLETT, ROBERT R., DICKNEITE, GERHARD, KLESEL, NORBERT, SCHORLEMMER, HANS ULRICH, SEIBERT, GERHARD, WINKLER, IRVIN, SCHRINNER, ELMAR

Journal:

The Journal of Antibiotics

Year:

1984

Language:

english

File:

PDF, 4.14 MB

english, 1984

19

Prediction of Broad-spectrum Pathogen Attachment to Coating Materials for Biomedical Devices

Mikulskis, Paulius, Hook, Andrew L., Dundas, Adam, Irvine, Derek J, Sanni, Olutoba, Anderson, Daniel G., Langer, Robert, Alexander, Morgan Russell, Williams, Paul, Winkler, David A.

Journal:

ACS Applied Materials & Interfaces

Year:

2017

Language:

english

File:

PDF, 624 KB

english, 2017

20

Association of Sickle Cell Trait With Ischemic Stroke Among African Americans

Hyacinth, Hyacinth I., Carty, Cara L., Seals, Samantha R., Irvin, Marguerite R., Naik, Rakhi P., Burke, Gregory L., Zakai, Neil A., Wilson, James G., Franceschini, Nora, Winkler, Cheryl A., David, Vic

Journal:

Year:

2018

Language:

english

File:

PDF, 261 KB

english, 2018

21

Association of sickle cell trait with atrial fibrillation: The REGARDS cohort

Douce, Daniel R., Soliman, Elsayed Z., Naik, Rakhi, Hyacinth, Hyacinth I., Cushman, Mary, Winkler, Cheryl A., Howard, George, Lange, Ethan M., Lange, Leslie A., Irvin, Marguerite R., Zakai, Neil A.

Journal:

Journal of Electrocardiology

Year:

2019

Language:

english

File:

PDF, 319 KB

english, 2019

22

APOL1 Nephropathy Risk Alleles and Mortality in African American Adults: A Cohort Study

Gutiérrez, Orlando M., Irvin, Marguerite R., Zakai, Neil A., Naik, Rakhi P., Chaudhary, Ninad S., Estrella, Michelle M., Limou, Sophie, Judd, Suzanne E., Cushman, Mary, Kopp, Jeffrey B., Winkler, Cher

Journal:

American Journal of Kidney Diseases

Year:

2019

Language:

english

File:

PDF, 333 KB

english, 2019

23

APOL1 Nephropathy Risk Alleles and Risk of Sepsis in Blacks

Chaudhary, Ninad S., Moore, Justin X., Zakai, Neil A., Judd, Suzanne E., Naik, Rakhi P., Limou, Sophie, Cushman, Mary, Lange, Leslie A., Wang, Henry E., Winkler, Cheryl A., Irvin, Marguerite R., Kopp,

Journal:

Clinical Journal of the American Society of Nephrology

Year:

2019

Language:

english

File:

PDF, 527 KB

english, 2019

24

APOL1 Nephropathy Risk Alleles and Risk of Sepsis in Blacks

Chaudhary, Ninad S., Moore, Justin X., Zakai, Neil A., Judd, Suzanne E., Naik, Rakhi P., Limou, Sophie, Cushman, Mary, Lange, Leslie A., Wang, Henry E., Winkler, Cheryl A., Irvin, Marguerite R., Kopp,

Journal:

Clinical Journal of the American Society of Nephrology

Year:

2019

File:

PDF, 527 KB

2019

25

Discovery of (meth)acrylate polymers that resist colonization by fungi associated with pathogenesis and biodeterioration

Vallieres, Cindy, Hook, Andrew L., He, Yinfeng, Crucitti, Valentina Cuzzucoli, Figueredo, Grazziela, Davies, Catheryn R., Burroughs, Laurence, Winkler, David A., Wildman, Ricky D., Irvine, Derek J., A

Journal:

Science Advances

Year:

2020

File:

PDF, 3.94 MB

2020